2005 Bone Fluid Flow Workshop
Attendees of the Seventh International Bone Fluid Flow Workshop, New York City, September 20-21:
FRONT ROW: Yi-Xian Qin, Ed Guo, Chris Jacobs, Mitch Schaffler, Kenneth McLeod, Steve Cowin, Lynda Bonewald, Shelly Weinbaum, Howard Winet, Henry Donahue, Robert Majeska, Jenneke Kline-Nulend, Aviral Vatsa. SECOND ROW: Laoise McNamara, Susannah Fritton, Alesha Castillo, Ryan Riddle, Jonathan Kaufman, Chuck Seegert, Theo Smit , Ken Myers, Cesare Ciani, Carmen Huesa , Cor Semeins, Jean Jiang, Dawei Liu, Larry Swain. THIRD ROW: Xiaobing Zhang, Young J. Yoon, Hoyan Lam, Damian Genetos, Luis Cardoso, Ravi Patel, Eric Anderson, Yilin Wang, Yuefeng Han, Dajun Zhang, Gregory Yourek, Agnès Rémond, Mel Bacabac, Zafrir Bechor.
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Invited Speakers Presenter: Lynda Bonewald, University of Missouri at Kansas City
Osteocytes are dynamic, not passive cells in their response to strain and remodeling of their microenvironment
LF Bonewald, J Feng, SE Harris, JX Jiang, S Kotha, N Lane, D Nicolella, E Sprague Presenter: Henry Donahue, Pennsylvania State University
Fluid flow activation of gap junctional communication and hemichannel activity in bone cells
HJ Donahue, AF Taylor, MM Saunders, DC Genetos, RC Riddle Presenter: Susannah Fritton, City College of New York
Osteocyte lacunar and canalicular structure
SP Fritton, T Beno, C Ciani, SB Doty Presenter: X. Edward Guo, Columbia University
Substrate modulation of osteoblast modulus and response to mechanical stimuli
E Takai, KD Costa, CT Hung, XE Guo Presenter: Christopher Jacobs, Stanford University
Bone cell mechanotransduction via loading-induced oscillatory fluid flow
C Jacobs, J Rodriquez, N Batra, L You, Y Li, J You, C Yellowley, H Donahue Presenter: Jean Jiang, University of Texas Health Science Center, San Antonio
Fluid flow shear stress induces the assembly of Cx43-forming hemichannels responsible for the release of PGE2 in osteocytes
PP Cherian, AJ Siller-Jackson, S Burra, S Gu, LF Bonewald, E Sprague, JX Jiang Presenter: Jenneke Klein-Nulend, ACTA-Vrije Universiteit, Amsterdam
Nitric oxide production by bone cells in response to mechanical vibration
J Klein-Nulend, RG Bacabac Presenter: Kenneth McLeod, State University of New York at Binghamton
Understanding osteopenia in the context of interstitial fluid flow
KJ McLeod Presenter: Anthony Mikos, Rice University
Modulation of cell differentiation in bone tissue engineering constructs cultured in a flow perfusion bioreactor
HL Holtorf, JA Jansen, AG Mikos Presenter: Yi-Xian Qin, State University of New York at Stony Brook
Skeletal muscle dynamics generated fluid flow in bone and its role in adaptation
Y-X Qin, H Lam, L Orzechowski, Y Xia, M Zhang Presenter: Theo Smit, Vrije Universiteit Medical Centre, Amsterdam
Bone apposition in a remodeling osteon is related to matrix shear strain, not fluid flow
TH Smit, RGM Breuls Presenter: Liyun Wang, Mount Sinai School of Medicine, New York
Investigating the structure of osteocytic pericellular matrix based on diffusion measurements in the bone lacunar-canalicular system
L Wang, Y Wang, Y Han, RJ Majeska, MB Schaffler Presenter: Sheldon Weinbaum, City College of New York
Mechanotransduction and strain amplification in bone cell processes
Y Han, S Cowin, M Schaffler, S Weinbaum Presenter: Howard Winet, Orthopaedic Hospital/University of California at Los Angeles
Evidence for muscle pump-generated intravascular pressure as a driving force contributor to bone intersititial fluid flow
C Caulkins-Pennell, H Winet Student Presentations Presenter: Eric J. Anderson, Case Western Reserve University
Fluid modeling of the lacunocanalicular network and imparted cellular-level forces
EJ Anderson, ML Knothe Tate Presenter: R. G. Bacabac, Vrije Universiteit
Characterizing the viscoelasticity and probing the mechano-activity of bone cells by two-particle microrheology
RG Bacabac, DS Mizuno, ThH Smit, JJWA van Loon, F MacKintosh, CF Schmidt, J Klein-Nulend Presenter: Zafrir Bechor, University of Melbourne
Intracortical third metacarpal bone hydrostatic pressure and fluid drainage effect on ultrasound velocity
Z Bechor, J Merritt, HMS Davies Presenter: Uday Chippada, Rutgers University
SMD studies of effects of structural water on the stiffness of collagen
U Chippada, D Zhang Presenter: Carmen Huesa, University of Aberdeen
Role of caveolin-1 in regulation of eNOS activation in osteoblastic cells
C Huesa, MH Helfrich, RM Aspden Presenter: Ho-Yan Lam, State University of New York at Stony Brook
Cyclic intramedullary pressure fluid stimulation alters nutrient artery morphology
HY Lam, P Brink, C Rubin, YX Qin Presenter: Kenneth A. Myers, University of Calgary
Effect of 1alpha,25 dihydroxyvitamin D3 treatment on the shear stress mechanosensitivity of an osteoblast-like cell line
KA Myers, NG Shrive, DA Hart Presenter: R. B. Patel, Case Western Reserve University
Measuring permeability and anisotropy effects of cortical bone using FRAP
RB Patel, JM O’Leary, ML Knothe Tate Presenter:Agnès Rémond, University of Paris
Mixture theory for multiphase flow: application to bone interstitial fluid
A Rémond, S Naïli, S Cowin Presenter: CM Semeins, Universiteit van Amsterdam and Vrije Universiteit
TNF-alpha induced apoptosis of osteocytes is inhibited by mechanical loading
CM Semeins, SD Tan, ALJJ Bronckers, AM Kuijpers-Jagtman, JC Maltha, JW von den Hoff, V Everts, J Klein-Nulend Presenter: Vikram Sreedharan, Rutgers University
Electrical response of a circular cell monolayer to an axisymmetric, low-frequency, oscillatory extracellular electrical field
V Sreedharan, D Zhang Presenter: A. Vasta, ACTA-UvA and Vrije Universiteit
Intercellular signaling in osteocytes after mechanical stimulation
A Vatsa, D Mizuno, TH Smit, CF Schmidt, FC MacKintosh, J Klein-Nulend Presenter: Gregory Yourek, University of Illinois at Chicago
Responses to fluid flow during early osteogenic differentiation of mesenchymal stem cells
G Yourek, GC Reilly, SM McCormick, JJ Mao |
